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Takuo Hayashi Selected Research

agerafenib

12/2020RET inhibition in novel patient-derived models of RET-fusion positive lung adenocarcinoma reveals a role for MYC upregulation.
6/2017Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations.

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Takuo Hayashi Research Topics

Disease

53Neoplasms (Cancer)
04/2024 - 01/2006
15Adenocarcinoma of Lung
04/2023 - 01/2013
12Adenocarcinoma
11/2023 - 01/2015
10Lymphangioleiomyomatosis (Lymphangiomyomatosis)
04/2024 - 07/2009
10Lung Neoplasms (Lung Cancer)
04/2024 - 06/2017
9Neoplasm Metastasis (Metastasis)
11/2023 - 01/2012
7Tuberous Sclerosis (Bourneville's Disease)
04/2024 - 09/2010
7Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2024 - 01/2018
5Sarcoma (Soft Tissue Sarcoma)
11/2023 - 10/2019
4Disease Progression
03/2024 - 01/2013
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2023 - 11/2012
4Carcinoma (Carcinomatosis)
09/2023 - 01/2012
4Stomach Neoplasms (Stomach Cancer)
01/2023 - 09/2013
4Lymphatic Metastasis
01/2021 - 01/2013
4Cysts
01/2021 - 01/2013
4Microsatellite Instability
01/2021 - 01/2017
3Carcinogenesis
04/2024 - 02/2014
3Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2024 - 10/2011
3Colorectal Neoplasms (Colorectal Cancer)
11/2023 - 06/2011
3Breast Neoplasms (Breast Cancer)
09/2023 - 10/2022
3Infections
01/2022 - 01/2003
3Hyperplasia
09/2021 - 09/2010
2Malignant Mesothelioma
02/2024 - 08/2021
2Urinary Bladder Neoplasms (Bladder Cancer)
11/2023 - 01/2022
2Brain Neoplasms (Brain Tumor)
09/2023 - 10/2021
2Interstitial Lung Diseases (Interstitial Lung Disease)
02/2023 - 11/2021
2Adenoma (Adenomas)
01/2023 - 02/2016
2Osteosarcoma (Osteogenic Sarcoma)
01/2022 - 11/2019
2Mucinous Adenocarcinoma (Mucinous Carcinoma)
06/2021 - 01/2021
2Leiomyosarcoma
04/2021 - 01/2021
2Lung Diseases (Lung Disease)
01/2021 - 04/2018
2Melanoma (Melanoma, Malignant)
01/2021 - 01/2012
1Erdheim-Chester Disease
03/2024
1Margins of Excision
01/2024
1Non-Muscle Invasive Bladder Neoplasms
11/2023
1Ataxia Telangiectasia (Louis Bar Syndrome)
11/2023
1Angiomyolipoma
11/2023
1Mastitis
11/2023
1Spontaneous Remission
11/2023
1Leiomyoma (Uterine Fibroids)
11/2023

Drug/Important Bio-Agent (IBA)

16Proteins (Proteins, Gene)FDA Link
02/2024 - 09/2010
10Biomarkers (Surrogate Marker)IBA
11/2023 - 01/2013
8lipoarabinomannan (LAM)IBA
04/2024 - 07/2009
8Phosphotransferases (Kinase)IBA
11/2023 - 01/2017
7DNA (Deoxyribonucleic Acid)IBA
02/2024 - 01/2017
7MucinsIBA
01/2023 - 01/2006
6Immune Checkpoint InhibitorsIBA
03/2024 - 01/2017
6Tyrosine Kinase InhibitorsIBA
10/2021 - 01/2020
5pembrolizumabIBA
03/2024 - 02/2019
5trans-sodium crocetinate (crocetin)IBA
11/2023 - 09/2010
4RNA (Ribonucleic Acid)IBA
11/2023 - 04/2021
4Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
11/2023 - 10/2020
4CateninsIBA
11/2023 - 06/2011
4Messenger RNA (mRNA)IBA
01/2022 - 11/2020
3tyrosine receptor (receptor, tyrosine)IBA
11/2023 - 11/2020
3Anaplastic Lymphoma KinaseIBA
11/2023 - 05/2018
3SteroidsIBA
11/2023 - 11/2021
3Thyroid Nuclear Factor 1IBA
04/2023 - 01/2021
3Indicators and Reagents (Reagents)IBA
02/2023 - 09/2017
3B7-H1 AntigenIBA
12/2022 - 11/2021
3Formaldehyde (Formol)FDA Link
01/2022 - 04/2019
3ParaffinIBA
01/2022 - 04/2019
2NucleotidesIBA
11/2023 - 04/2019
2Gonadotropin-Releasing Hormone (GnRH)FDA Link
11/2023 - 01/2017
2TubulinIBA
11/2023 - 01/2015
2GlycogenIBA
09/2023 - 01/2018
2Trastuzumab (Herceptin)FDA Link
03/2023 - 01/2018
2Protein Isoforms (Isoforms)IBA
01/2022 - 01/2021
2larotrectinibIBA
11/2021 - 10/2019
2Tyrosine (L-Tyrosine)FDA Link
04/2021 - 01/2017
2phosphatidyl-N-monomethylaminoethanolIBA
01/2021 - 01/2012
2agerafenibIBA
12/2020 - 06/2017
2cabozantinibIBA
12/2020 - 01/2017
2GlypicansIBA
09/2020 - 01/2018
2DenosumabFDA Link
01/2020 - 01/2019
2Vascular Endothelial Growth Factor DIBA
01/2020 - 04/2016
2Gefitinib (Iressa)FDA Link
11/2019 - 11/2017
2Transcription Factor 4IBA
11/2019 - 01/2018
2Galectin 4 (LGALS4)IBA
09/2017 - 01/2013
2Thymidylate SynthaseIBA
09/2017 - 01/2015
2Sirolimus (Rapamycin)FDA Link
01/2017 - 07/2014
1LigandsIBA
03/2024
1Adrenal Cortex Hormones (Corticosteroids)IBA
03/2024
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
02/2024
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2024
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2024
1Phenobarbital (Luminal)FDA Link
11/2023
1Type 3 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 3)IBA
11/2023
1Lysine (L-Lysine)FDA Link
11/2023
1Immunoglobulin G (IgG)IBA
11/2023
1Hormones (Hormone)IBA
11/2023
1Doxorubicin (Adriamycin)FDA LinkGeneric
11/2023

Therapy/Procedure

21Therapeutics
11/2023 - 01/2017
11Drug Therapy (Chemotherapy)
11/2023 - 01/2015
4Immunotherapy
11/2023 - 10/2021
3Precision Medicine
06/2021 - 04/2019
2Hysterectomy
11/2023 - 01/2014
2Operative Surgical Procedures
05/2023 - 01/2003
2Radiotherapy
10/2021 - 11/2020
1Segmental Mastectomy (Lumpectomy)
01/2024